In the WebStandards igniter workshop I didn't rely on any external library or framework and focussed on web standards only.
Older browsers may not support recent APIs and may require "patching", also known as polyfills.
In these 2:20 mins screencast I implement, install and use an imaginary
Web Apps, SPA, PWA with vanilla Java Script (ES 6+), CSS 3 and WebStandards only. As simple as possible, but not simpler. See you at: (Progressive) Web apps, Single Page Apps and WebStandards airhacks workshops at MUC airport, Winter Edition
airhacks.fm the podcast:
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